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Once xylazine gains access to the vascular system, it is distributed within the blood, allowing xylazine to enter the heart, lungs, liver, and kidney. [26] In non-fatal cases, the blood plasma concentrations range from 0.03 to 4.6 mg/L. [ 3 ] Xylazine diffuses extensively and penetrates the blood–brain barrier , as might be expected due to ...
The bladder is an organ that stores urine until it is released from the body. Several conditions can affect the bladder including urinary tract infections, bladder stones, bladder cancer, overactive bladder, cystitis, interstitial cystitis, abscess, fistula, and urinary incontinence. [4] [5] [1]
As of 2019, about 94 million men aged 40 years and older are affected globally. [3] BPH typically begins after the age of 40. [1] The prevalence of clinically diagnosed BPH peaks at 24% in men aged 75–79 years. [3] Based on autopsy studies, half of males aged 50 and over are affected, and this figure climbs to 80% after the age of 80. [3]
Urologic oncology concerns the surgical treatment of malignant genitourinary diseases such as cancer of the prostate, adrenal glands, bladder, kidneys, ureters, testicles, and penis, as well as the skin and subcutaneous tissue and muscle and fascia of those areas (that particular subspecialty overlaps with dermatological oncology and related ...
Kidney disease usually causes a loss of kidney function to some degree and can result in kidney failure, the complete loss of kidney function. Kidney failure is known as the end-stage of kidney disease, where dialysis or a kidney transplant is the only treatment option. Chronic kidney disease causes the gradual loss of kidney function over time.
For most patients, a GFR over 60 (mL/min)/(1.73 m 2) is adequate. But significant decline of the GFR from a previous test result can be an early indicator of kidney disease requiring medical intervention. The sooner kidney dysfunction is diagnosed and treated the greater odds of preserving remaining nephrons, and preventing the need for dialysis.