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  2. Intracranial pressure - Wikipedia

    en.wikipedia.org/wiki/Intracranial_pressure

    This is rarely required outside brain injury and brain surgery settings. [citation needed] In situations when only small amounts of CSF are to be drained to reduce ICP's (e.g. in idiopathic intracranial hypertension), drainage of CSF via lumbar puncture can be used as a treatment. Non-invasive measurement of intracranial pressure is being ...

  3. Therapeutic drug monitoring - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_drug_monitoring

    Nowadays, most other drugs can be readily measured in blood or plasma using versatile methods such as liquid chromatography–mass spectrometry or gas chromatography–mass spectrometry, which progressively replaced high-performance liquid chromatography. Yet, TDM is not limited to the provision of precise and accurate concentration measurement ...

  4. Non-invasive measurement of intracranial pressure - Wikipedia

    en.wikipedia.org/wiki/Non-invasive_measurement...

    First, a measurement of the position of the tympanic membrane needs to be obtained while ICP is zero (denoted as the baseline position). Equalization of ICP to the atmospheric pressure according to the inventor can be achieved non-invasively by tilting the head up, or the measurement can be taken during a neurosurgical operation.

  5. Neuroinflammation - Wikipedia

    en.wikipedia.org/wiki/Neuroinflammation

    Neuroinflammation is widely regarded as chronic, as opposed to acute, inflammation of the central nervous system. [5] Acute inflammation usually follows injury to the central nervous system immediately, and is characterized by inflammatory molecules, endothelial cell activation, platelet deposition, and tissue edema. [6]

  6. Anti-inflammatory - Wikipedia

    en.wikipedia.org/wiki/Anti-inflammatory

    [23] [24] [25] They may also have applications in the treatment of neuroinflammation. [13] [16] The anti-inflammatory effects of psychedelics may be involved in the effects of psychedelic microdosing. [26] [27] Relatedly, LSD microdosing is being studied in the treatment of Alzheimer's disease for its anti-inflammatory effects. [28] [29]

  7. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    Another use is in the therapeutic drug monitoring of drugs with a narrow therapeutic index. For example, gentamicin is an antibiotic that can be nephrotoxic (kidney damaging) and ototoxic (hearing damaging); measurement of gentamicin through concentrations in a patient's plasma and calculation of the AUC is used to guide the dosage of this drug ...

  8. Hospital medication errors left SoCal patients at risk. One ...

    www.aol.com/news/hospital-medication-errors-left...

    State regulators faulted two hospitals in Southern California for medication errors that put patients at risk, including one who suffered a brain bleed after receiving repeated doses of blood thinner.

  9. Cmax (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Cmax_(pharmacology)

    Short term drug side effects are most likely to occur at or near the C max, whereas the therapeutic effect of drug with sustained duration of action usually occurs at concentrations slightly above the C min. [citation needed] The C max is often measured in an effort to show bioequivalence (BE) between a generic and innovator drug product. [4]