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Immunologic pregnancy tests were introduced in 1960 when Wide and Gemzell presented a test based on in-vitro hemagglutination inhibition. This was a first step away from in-vivo pregnancy testing [42] [43] and initiated a series of improvements in pregnancy testing leading to the contemporary at-home testing. [43]
The triple test, also called triple screen, the Kettering test or the Bart's test, is an investigation performed during pregnancy in the second trimester to classify a patient as either high-risk or low-risk for chromosomal abnormalities (and neural tube defects). The term "multiple-marker screening test" is sometimes used instead.
Many point-of-care test systems are realized as easy-to-use membrane-based test strips, often enclosed by a plastic test cassette. [2] This concept often is realized in test systems for detecting pathogens, the most common being COVID-19 rapid tests. Very recently such test systems for rheumatology diagnostics have been developed, too. [12]
Pregnancy tests fall into two categories: at-home urine tests and the in-office blood test. At-home urine tests have different thresholds for the level of hCG they’re looking for, Dr. Ahmad says.
Many screening tests are inaccurate, so one worrisome test result frequently leads to additional, more invasive tests. If prenatal testing confirms a serious disability, many parents are forced to decide whether to continue the pregnancy or seek an abortion. The "option" of screening becomes an unexpected requirement to decide. See wrongful ...
The frog test had been a highly dependable pregnancy testing method since the 1930s until the immunological test was presented in the 1960s. [12] Pharmacists would inject the female's early urine sample into the frogs and confirm their pregnancy with the spawning of eggs within 18 hours. However, there was a critical prerequisite for accurately ...