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Wernicke-Korsakoff syndrome (WKS) is the combined presence of Wernicke encephalopathy (WE) and alcoholic Korsakoff syndrome (AKS [clarification needed]). Due to the close relationship between these two disorders, people with either are usually diagnosed with WKS as a single syndrome. It mainly causes vision changes, ataxia and impaired memory. [2]
When it occurs simultaneously with alcoholic Korsakoff syndrome it is known as Wernicke–Korsakoff syndrome. [3] [4] Classically, Wernicke encephalopathy is characterised by a triad of symptoms: ophthalmoplegia, ataxia, and confusion. Around 10% of patients exhibit all three features, and other symptoms may also be present. [5]
Korsakoff syndrome (KS) [1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation. This neurological disorder is caused by a deficiency of thiamine (vitamin B 1 ) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol . [ 2 ]
[5] Studies show there is a correlation between brain lesion and language, speech, and category-specific disorders. Wernicke's aphasia is associated with anomia, unknowingly making up words , and problems with comprehension. The symptoms of Wernicke's aphasia are caused by damage to the posterior section of the superior temporal gyrus.
Studies have suggested that conduction aphasia is a result of damage specifically to the left superior temporal gyrus and/or the left supramarginal gyrus. [5] The classical explanation for conduction aphasia is a disconnection between the brain areas responsible for speech comprehension (Wernicke's area) and that of speech production (Broca's ...
Silica nanoparticles induce coagulation through contact activation of coagulation factor XII (Hageman factor). [2] The silica particles are desiccants, which adsorb and hold water vapor. [ 3 ] This is used in the tubes so the blood adheres to the surface of the tiny silica particles and begins to clot.
Wernicke-Korsakov syndrome or Polioencephalitis haemorrhagica superior associated with Korsakov's psychosis: A condition characterized by nystagmus, ocular and Conjugate gaze palsy, ataxia and psychosis due to nutritional deficiency, more specifically of thiamine and observed mainly, though not exclusively, in alcoholics.
Carl (or Karl) [a] Wernicke (/ ˈ v ɛər n ɪ k ə /; German: [ˈvɛɐ̯nɪkə]; 15 May 1848 – 15 June 1905) was a German physician, anatomist, psychiatrist and neuropathologist.He is known for his influential research into the pathological effects of specific forms of encephalopathy and also the study of receptive aphasia, both of which are commonly associated with Wernicke's name and ...