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Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]
Torcetrapib (CP-529,414, Pfizer) was a drug being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease.Its development was halted in 2006 when phase III studies showed excessive all-cause mortality in the treatment group receiving a combination of atorvastatin (Lipitor) and torcetrapib.
In 1996, Warner-Lambert entered into a co-marketing agreement with Pfizer to sell Lipitor, and in 2000, Pfizer acquired Warner-Lambert for $90.2 billion. [116] [106] [112] [113] Lipitor was on the market by 1996. [114] [117] By 2003, Lipitor had become the best selling pharmaceutical in the United States. [110]
Pfizer (NYS: PFE) used to sell Lipitor exclusively in the United States. And it was a huge component of the company's revenue and earnings. Honest. I swear. You certainly wouldn't know it from the ...
Lately, almost every day we've heard of a new Pfizer (NYS: PFE) strategy for hanging on to Lipitor sales after the drug faces generic competition. Discounts, co-pay cards, rebates, conversion to ...
You can't blame Pfizer (NYS: PFE) for trying to squeeze every last bit of sales from Lipitor. And on the face of it, a bid to move the megablockbuster cholesterol drug over the counter seems logical.
Drug interactions are possible, but studies have not shown that these statins increase exposure to ciclosporin. [60] HIV-positive people taking protease inhibitors: Atorvastatin, pravastatin or fluvastatin: Negative interactions are more likely with other choices. [61] Persons taking gemfibrozil, a non-statin lipid-lowering drug Atorvastatin
But this time it's Pfizer (NYS: PFE) and Merck (NYS: Usually, it's a branded drugmaker fighting off a generics challenge from a copycat drugmaker. Pfizer Sues Merck to Block Lipitor/Zetia Combo Pill