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Oclacitinib lacks the side effects that most JAK inhibitors have in humans; instead, side effects are infrequent, mild, and mostly self-limiting. [13] [14] [16] The most common side effects are gastrointestinal problems (vomiting, diarrhea, and appetite loss) and lethargy. The GI problems can sometimes be alleviated by giving oclacitinib with food.
Effects generally begin within thirty minutes and last for about a day. [6] The degree of benefit is similar to other antihistamines such as diphenhydramine, which is a first-generation antihistamine. [6] Common side effects include sleepiness, dry mouth, headache, and abdominal pain. [6]
It should be 100% diphenhydramine, not Benadryl-D or any other product. Although Benadryl is safe, giving your dog decongestants like pseudoephedrine can cause: Depression. Weakness. Vomiting ...
Hydroxyzine works by blocking the effects of histamine. [9] It is a first-generation antihistamine in the piperazine family of chemicals. [8] [4] Common side effects include sleepiness, headache, and dry mouth. [8] [9] Serious side effects may include QT prolongation. [9] It is unclear if use during pregnancy or breastfeeding is safe. [8]
The effects of the brain activity can interfere with the REM (rapid eye movement) part of sleep, where the majority of dreams and nightmares occur, which is around 90 minutes into sleep. REM is ...
The death of a loved one or a stressful life event can be enough to cause a nightmare but conditions such as post-traumatic stress disorder and other psychiatric disorders have been known to cause nightmares as well. [14] If the individual is on medication, the nightmares may be attributed to some side effects of the drug.
Nightmares; Abnormality of cerebrospinal fluid proteins; Dysphoria [Note 35] Catatonic excitement; Narrow angle glaucoma; Optic atrophy; Pigmentary retinopathy; Amenorrhoea [Note 36] Infertility; Tardive dyskinesia [Note 37]
Doxylamine is also a potent anticholinergic, meaning that it causes delirum at high doses—i.e., at much higher doses than recommended. [8] (Specifically it is an antagonist of the muscarinic acetylcholine receptors M 1 through M 5.) These sedative and deliriant effects have in some cases led to using the drug recreationally.