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Titled “Rationale for the Use of Topical Calcineurin Inhibitors in the Management of Oral Lichen Planus and Mucosal Inflammatory Diseases,” the paper focuses on non-steroid treatments for oral lichen planus (OLP), particularly topical calcineurin inhibitors (TCIs) such as tacrolimus. TCIs are non-steroidal medications used to treat ...
Currently, there are no FDA-approved pharmacotherapies for Oral Lichen Planus, and LP-310 is the only topical treatment in development for OLP. About the Study The Oral Lichen Planus Clinical Trial is a multicenter, dose-ranging study involving adult male and female subjects (18 years and older) with symptomatic OLP. This study will evaluate ...
Dr. Michael Chancellor, Chief Medical Officer of Lipella Pharmaceuticals, stated: “We are pleased to introduce this critical registry with the aim of increasing awareness and accelerating research into Oral Lichen Planus, a condition that urgently requires effective treatment options for millions of sufferers across the globe.”
Treatment: Lichen planus doesn't have a cure, but some treatments can make you feel more comfortable and speed up the healing process. Those include antihistamines and topical or oral steroids ...
Lichen planus may be categorized as affecting mucosal or cutaneous surfaces.. Cutaneous forms are those affecting the skin, scalp, and nails. [10] [11] [12]Mucosal forms are those affecting the lining of the gastrointestinal tract (mouth, pharynx, esophagus, stomach, anus), larynx, and other mucosal surfaces including the genitals, peritoneum, ears, nose, bladder and conjunctiva of the eyes.
It has been proven to be effective in various inflammatory skin diseases, e.g., seborrheic dermatitis, [2] cutaneous lupus erythematosus, [3] oral lichen planus, [4] vitiligo, [5] and psoriasis. [6] [7] Tacrolimus and pimecrolimus are both calcineurin inhibitors and function as immunosuppressants. [8]