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Yes, metformin treatment has been shown to lower risk of heart-related events in people with type 2 diabetes by improving blood fat levels, reducing inflammation, and lowering blood pressure ...
Metformin is more commonly associated with gastrointestinal adverse effects than most other antidiabetic medications. [46] [77] The most serious potential adverse effect of metformin is lactic acidosis; this complication is rare, and seems to be related to impaired liver or kidney function.
Are Diabetes Weight Loss Drugs Safe? Generally speaking, GLP-1s, GIP/GLP-1s, and metformin are considered safe and effective when used as prescribed.
Among other things, the medication may help lower the amount of fat in the blood, a person's body weight and their blood pressure. This may be tied to metformin’s ability to lower blood sugar ...
No effect on blood pressure; No detrimental effect on low-density lipoprotein; Lower risk of gastrointestinal side effects than metformin; Convenient dosing; Cause an average of 2–5 kg weight gain; Increase the risk of hypoglycemia; Glyburide increases risk of hypoglycemia slightly more compared to glimepiride and glipizide; Metformin
Metformin is an example of a class of medicine called biguanides. [34] The medication works by reducing the new creation of glucose from the liver and by reducing absorption of sugar from food. [34] In addition, the medication also works to help increase the effects of insulin on muscle cells, which take in glucose. [35]