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Fezolinetant, sold under the brand name Veozah among others, is a medication used for the treatment of hot flashes (vasomotor symptoms) due to menopause. [4] [10] It is a small-molecule, orally active, selective neurokinin-3 (NK 3) receptor antagonist which is under development for the treatment of sex hormone-related disorders.
While a 2018 review found that taking progesterone and estrogen together can decrease this risk, [47] other reviews reported an increased risk of blood clots and pulmonary embolism when estrogen and progestogen were combined, particularly when treatment was started 10 years or more after menopause and when the women were older than 60 years.
The slow release of estradiol valerate is caused by the increased lipophilicity of the medication, which in turn is due to its long fatty acid valeric acid ester moiety. [4] The elimination half-life of estradiol valerate in oil by intramuscular injection (brand names Estradiol-Depot 10 mg, Progynon Depot-10) is about 3.5 days, with a range of ...
The most widely used and most effective treatment for many perimenopause and menopause symptoms, including hot flashes and vaginal dryness, is hormone therapy (HT), says Nanette Santoro, M.D ...
Hormone replacement therapy (HRT), also known as menopausal hormone therapy (MHT), is for women with menopausal symptoms. It is based on the idea that the treatment may prevent discomfort caused by diminished circulating estrogen and progesterone hormones, or in the case of the surgically or prematurely menopausal, that it may prolong life and may reduce incidence of dementia. [1]
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