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Monoterpenes myrcene and sesquiterpenes β-caryophyllene (binds to the human CB2 cannabinoids receptor) and α-humulene are the most common terpene compounds, and are present in most varieties of cannabis strains. The lack of exact standards makes it sometimes difficult for scientists to classify new terpenes.
The phrase entourage effect was introduced in 1999. [9] [10] While originally identified as a novel method of endocannabinoid regulation by which multiple endogenous chemical species display a cooperative effect in eliciting a cellular response, the term has evolved to describe the polypharmacy effects of combined cannabis phytochemicals or whole plant extracts. [11]
Traditional heirloom strains of cannabis and contemporary hybrid varieties vary broadly because terpenes in the essential oils of the flowers, which give the buds their fragrance, and the ratio of cannabinoids, the more than 100 different therapeutically-active compounds, are infinitely variable.
The strain is a high quality bud originating in northeast Thailand, where it was grown by hill tribes since antiquity. The name comes from a traditional Thai method of preparing cannabis to be smoked, which involved wrapping cannabis bud around a stick. [ 90 ]
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Terpenes (98) Vitamins (1) Cannabis also produces numerous volatile sulfur compounds that contribute to the plant's skunk-like aroma, with Prenylthiol (3-methyl-2-butene-1-thiol) identified as the primary odorant. [15] These compounds are found in much lower concentrations than the major terpenes and sesquiterpenes.
The terpene alpha-pinene is a major component of the common solvent, turpentine. The one terpene that has major applications is natural rubber (i.e., polyisoprene). The possibility that other terpenes could be used as precursors to produce synthetic polymers has been investigated. Many terpenes have been shown to have pharmacological effects.
Cannabis strains is a popular name to refer to plant varieties of the monospecific genus Cannabis sativa L.. They are either pure or hybrid varieties of the plant, which encompasses various sub-species C. sativa , C. indica , and C. ruderalis .