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Endometrial hyperplasia is a condition of excessive proliferation of the cells of the endometrium, or inner lining of the uterus.. Most cases of endometrial hyperplasia result from high levels of estrogens, combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this tissue.
Development of an endometrial hyperplasia (overgrowth of endometrial cells) is a significant risk factor because hyperplasias can and often do develop into adenocarcinoma, though cancer can develop without the presence of a hyperplasia. [20]
Endometrial Topography Functional Category Treatment Benign endometrial hyperplasia: Diffuse: Hormone (estrogen) Effect: Hormonal therapy EIN, Endometrial Intraepithelial Neoplasia: Focal progressing to diffuse (clonal) Precancer: Hormonal or surgical Endometrial Adenocarcinoma: Focal progressing to diffuse (clonal) Cancer: Surgical stage-based
When endometrial cancer is caught in stages one or two, Dr. Ramirez says that treatment typically involves a total abdominal hysterectomy as well as a bilateral oophorectomy (a surgical procedure ...
(Endometrial cancer is a type of uterine cancer, the Cleveland Clinic explains, although the terms are often used interchangeably.) But the current guidelines that doctors and radiologists use to ...
The development of endometrial adenocarcinoma from endometrial hyperplasia is a typical example of how the effects of pathologic hyperplasia can lead to neoplasia, and females who exhibit hyperplasia of the endometrium are indeed more likely to develop cancer of these cells. [15]
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