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Tuberculosis (TB), also known colloquially as the " white death ", or historically as consumption, [8] is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. [1] Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1] Most infections show no symptoms, in which case it is known ...
According to the World Health Organization’s (WHO) Global Tuberculosis Report 2024, roughly 10.8 million people “fell ill” with the bacterial infection in 2023.
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [1][2] First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid.
Healed tuberculous cavity, where the entire left lung is destroyed. Post-tuberculosis lung disease (PTLD) is ongoing lung disease that is caused by tuberculosis (TB) but persists after the infection is cured. [1] PTLD can affect the airways, lung parenchyma, pulmonary vasculature, and pleura. [2]
A definitive diagnosis of tuberculosis can only be made by culturing Mycobacterium tuberculosis organisms from a specimen taken from the patient (most often sputum, but may also include pus, CSF, biopsied tissue, etc.). [1] A diagnosis made other than by culture may only be classified as "probable" or "presumed".
Up to 13 million people in the U.S. have latent tuberculosis infections, meaning the bacteria is inactive and the infected person doesn’t have symptoms and isn’t contagious. Around 5% to 10% ...
In 2014, results of a new DNA study of a tuberculosis genome reconstructed from remains in southern Peru suggest that human tuberculosis is less than 6,000 years old. Even if researchers theorise that humans first acquired it in Africa about 5,000 years ago, [1] there is evidence that the first tuberculosis infection happened about 9,000 years ago.
Cystic fibrosis (also known as CF or mucoviscidosis) is an autosomal recessive genetic disorder affecting most critically the lungs, and also the pancreas, liver, and intestine.