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It causes almost 10% of intellectual disability of otherwise unknown cause and can result in behavioral problems. [2] Some of the effects are permanent. [2] In severe cases, anemia, seizures, coma, or death may occur. [1] [2] Exposure to lead can occur by contaminated air, water, dust, food, or consumer products. [2]
Lead can cause severe damage to the brain and kidneys and, ultimately, death. By mimicking calcium, lead can cross the blood–brain barrier. It degrades the myelin sheaths of neurons, reduces their numbers, interferes with neurotransmission routes, and decreases neuronal growth. [265]
Blood lead level (BLL), is a measure of the amount of lead in the blood. [1] [2] Lead is a toxic heavy metal and can cause neurological damage, especially among children, at any detectable level. High lead levels cause decreased vitamin D and haemoglobin synthesis as well as anemia, acute central nervous system disorders, and possibly death. [3]
Over the long term, lead can cause neurocognitive deficits, ... "Lead can be damaging to the developing brain," Calello says. "While adults can have effects from excess lead exposure as well, the ...
Lead is widely understood to be toxic to multiple organs of the human body, particularly the human brain. Concerns about even low levels of exposure began in the 1970s; in the decades since, scientists have concluded that no safe threshold for lead exposure exists. [2] [3] The major source of lead exposure during the 20th century was leaded ...
Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse effects to prescription drugs, or exposure to extreme concentrations of any natural toxin such as cyanotoxins found in shellfish or freshwater ...
The most common causes of CKD are high blood pressure and diabetes, "which damage the small blood vessels and filtering units in the kidneys over time," says Nagata. Other potential causes he ...
Particulate exposure and increased risk of neurodegeneration [1]. Research indicates that living in areas of high pollution has serious long term health effects. Living in these areas during childhood and adolescence can lead to diminished mental capacity and an increased risk of brain damage.