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Pseudomonas aeruginosa in Petri dish. Pseudomonas aeruginosa is a common encapsulated, Gram-negative, aerobic–facultatively anaerobic, rod-shaped bacterium that can cause disease in plants and animals, including humans.
Pseudomonas infection refers to a disease caused by one of the species of the genus Pseudomonas. P. aeruginosa is a germ found in the environment and it is an opportunistic human pathogen most commonly infecting immunocompromised patients, such as those with cancer, diabetes, cystic fibrosis, [1] severe burns, AIDS, [2] or people who are very ...
Pseudomonas aeruginosa is highly contagious and has displayed resistance to antibiotic treatments, making it difficult to manage effectively. Some strains of Pseudomonas are known to target white blood cells in various mammal species, posing risks to humans, cattle, sheep, and dogs alike. [47]
Hot tub folliculitis, also called Pseudomonal folliculitis or Pseudomonas aeruginosa folliculitis, is a common type of folliculitis featuring inflammation of hair follicles and surrounding skin. [1]: 272 This condition is caused by an infection of the skin and hair follicles by the bacterium Pseudomonas aeruginosa.
Studies also suggest the emergence of antibiotic resistance in P. aeruginosa. [5] In 2000, the complete genome of a Pseudomonas species was sequenced; more recently, the genomes of other species have been sequenced, including P. aeruginosa PAO1 (2000), P. putida KT2440 (2002), P. fluorescens Pf-5 (2005), P. fluorescens PfO-1, and P. entomophila ...
Pseudomonas aeruginosa. The molecule 2-heptyl-3-hydroxy-4-quinolone, also named the Pseudomonas quinolone signal (PQS), has been discovered as an intracellular link between the two major quorum sensing systems of P. aeruginosa; the las and rhl systems. [1]
Pyocyanin (PCN −) is one of the many toxic compounds produced and secreted by the Gram negative bacterium Pseudomonas aeruginosa.Pyocyanin is a blue secondary metabolite, turning red below pH 4.9, with the ability to oxidise and reduce other molecules [2] and therefore kill microbes competing against P. aeruginosa as well as mammalian cells of the lungs which P. aeruginosa has infected ...
The Pseudomonas exotoxin (or exotoxin A) is an exotoxin produced by Pseudomonas aeruginosa. [1] Vibrio cholerae produces a similar protein called the Cholix toxin 2] It inhibits elongation factor-2. It does so by ADP-ribosylation of EF2 using NAD+. This then causes the elongation of polypeptides to cease.