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The results showed no statistically significant difference between renal denervation and the sham procedure. [4] Following the publication of Symplicity HTN-3 the Joint UK Societies produced a consensus statement that did not recommend the use of renal denervation for treatment of resistant hypertension in routine clinical practice.
Renal denervation involves using radio frequency or ultrasound to eliminate the sympathetic nerve supply to the kidney wall, aiming to lower blood pressure and treat chronic hypertension. [11] Renal denervation has become less common in recent years due to new evidence indicating that the procedure does not significantly lower blood pressure.
Endoscopic thoracic sympathectomy (ETS) is a surgical procedure in which a portion of the sympathetic nerve trunk in the thoracic region is destroyed. [1] [2] ETS is used to treat excessive sweating in certain parts of the body (focal hyperhidrosis), facial flushing, Raynaud's disease and reflex sympathetic dystrophy.
Highly selective vagotomy includes denervation of only the fundus and body (parietal cell-containing areas) of the stomach (also called parietal cell vagotomy). It preserves the nerve supply of the antrum and pylorus; a pyloric drainage procedure is not needed. It does not denervate the liver, biliary tree, pancreas, or small and large bowel.
Targeted lung denervation (TLD) is a procedure, that is currently being studied, to try to improve chronic obstructive pulmonary disease (COPD). [1] Evidence to support its use is insufficient as of 2015. [1] TLD is intended to block airway nerves of the parasympathetic nervous system to try to relax the airways. [2]
This procedure is mainly used only when other feasible approaches to pain management are unable to be used. [ 6 ] Lumbar sympathetic neurolysis is performed by using absolute alcohol, but other chemicals such as phenol, or other techniques such as radiofrequency or laser ablation have been studied.
Radiofrequency ablation (RFA), also called fulguration, [1] is a medical procedure in which part of the electrical conduction system of the heart, tumor, sensory nerves or a dysfunctional tissue is ablated using the heat generated from medium frequency alternating current (in the range of 350–500 kHz).
Patients with severe pain may need high-dose opioids daily or almost daily. Occasionally, people with LPHS require hospitalization for intravenous opioid therapy and control of nausea. Other treatments may include denervation, autotransplantation, renal neurectomy, or nephrectomy. Unfortunately symptoms often recur following these procedures.