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Mutations in the TATA box region affects the binding of the TATA-binding protein (TBP) for transcription initiation, which may cause carriers to have a disease phenotype. Gastric cancer is correlated with TATA box polymorphism. [39] The TATA box has a binding site for the transcription factor of the PG2 gene.
The TATA-binding protein (TBP) is a general transcription factor that binds to a DNA sequence called the TATA box. This DNA sequence is found about 30 base pairs upstream of the transcription start site in some eukaryotic gene promoters .
T-box transcription factor TBX5, (T-box protein 5) is a protein that in humans is encoded by the TBX5 gene. [ 5 ] [ 6 ] [ 7 ] Abnormalities in the TBX5 gene can result in altered limb development, Holt-Oram syndrome , Tetra-amelia syndrome , and cardiac and skeletal problems.
A common basal promoter is the TATAAAAAA sequence known as the TATA box. The TATA box is a complex with several different proteins including transcription factor II D (TFIID) which includes the TATA-binding protein (TBP) that binds to the TATA box along with 13 other proteins that bind to TBP. The TATA box binding proteins also include the ...
TATA-box binding protein like 2 is a protein that in humans is encoded by the TBPL2 gene. [5] The TBPL2 protein is also known as TBP-related factor 3 (TRF3) and TATA binding protein 2 (TBP2). The protein was independently discovered in three laboratories as a vertebrate-specific family member of TATA-binding protein (TBP).
T-box transcription factor TBX3 is a protein that in humans is encoded by the TBX3 gene. [1] [2] T-box 3 (TBX3) is a member of the T-box gene family of transcription factors which all share a highly conserved DNA binding domain known as the T-box. The T-box gene family consists of 17 members in mouse and humans that are grouped into five ...
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa, also known as TAF9, is a protein that in humans is encoded by the TAF9 gene. [ 5 ] [ 6 ] Function
107182 Ensembl ENSG00000095564 ENSMUSG00000040565 UniProt O14981 Q2M1V9 E9QAE3 RefSeq (mRNA) NM_003972 NM_001080706 RefSeq (protein) NP_003963 NP_003963.1 NP_001074175 Location (UCSC) Chr 10: 91.92 – 92.03 Mb Chr 19: 36.9 – 36.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse TATA-binding protein-associated factor 172 is a protein that in humans is encoded by the BTAF1 gene ...