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Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
Anthelmintic resistance in parasites is widespread; drug resistance exists in all livestock hosts and to all anthelmintic drug classes. [13] This is a major threat to the sustainability of modern ruminant livestock production, resulting in reduced productivity, compromised animal health and welfare, [ 12 ] and increased greenhouse gas emissions ...
Drugs are frequently used to kill parasites in the host. In earlier times, turpentine was often used for this, but modern drugs do not poison intestinal worms directly. Rather, anthelmintic drugs now inhibit an enzyme that is necessary for the worm to make the substance that prevents the worm from being digested.
The benzimidazole compounds albendazole (brand names e.g., Albenza, Eskazole, Zentel and Andazol) and mebendazole (brand names e.g., Ovex, Vermox, Antiox and Pripsen) are the most effective. [26] They work by inhibiting the microtubule function in the pinworm adults, causing glycogen depletion, [26] thereby effectively starving the parasite. [27]
Infection is typically treated with antiparasitic medication such as albendazole or mebendazole. [4] Rapid treatment may kill adult worms and thereby stop further worsening of symptoms. [4] Both medications are considered safe but have been associated with side effects such as bone marrow suppression. [4]
The parasite can cause canine schistosomiasis, an illness that affects the liver and intestines of dogs, according to Dillman. Read more: It hit 120 degrees in this California town. For the ...
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The most common treatments for hookworm are benzimidazoles, specifically albendazole and mebendazole. BZAs kill adult worms by binding to the nematode's β-tubulin and subsequently inhibiting microtubule polymerization within the parasite. [14] In certain circumstances, levamisole and pyrantel pamoate may be used. [12]