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TM-score between two protein structures (e.g., a template structure and a target structure) is defined by = [+ (())] where is the length of the amino acid sequence of the target protein, and is the number of residues that appear in both the template and target structures.
I-TASSER is a template-based method for protein structure and function prediction. [1] ... predicted TM-score and RMSD for the first model, ...
By the original design the GDT algorithm calculates 20 GDT scores, i.e. for each of 20 consecutive distance cutoffs (0.5 Å, 1.0 Å, 1.5 Å, ... 10.0 Å). [2] For structure similarity assessment it is intended to use the GDT scores from several cutoff distances, and scores generally increase with increasing cutoff.
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TM-align, for instance, is particularly robust in quantifying comparisons between sets of proteins with great disparities in sequence lengths, but it only indirectly captures hydrogen bonding or secondary structure order conservation which might be better metrics for alignment of evolutionarily related proteins.
TM-score – a different structure comparison measure; Longest continuous segment (LCS) — A different structure comparison measure; Global distance calculation (GDC_sc, GDC_all) — Structure comparison measures that use full-model information (not just α-carbon) to assess similarity
1 Max in TM-score equation. 1 comment. Toggle the table of contents. Talk: Template modeling score. Add languages. Page contents not supported in other languages.
WASHINGTON (Reuters) -China said on Monday it is willing to repatriate confirmed Chinese nationals from the United States, as U.S. President Donald Trump has threatened tariffs and sanctions on ...