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It is a type of organelle made up of two subunits – rough endoplasmic reticulum (RER), and smooth endoplasmic reticulum (SER). The endoplasmic reticulum is found in most eukaryotic cells and forms an interconnected network of flattened, membrane-enclosed sacs known as cisternae (in the RER), and tubular structures in the SER.
The unusual microscopic anatomy of a muscle cell gave rise to its terminology. The cytoplasm in a muscle cell is termed the sarcoplasm; the smooth endoplasmic reticulum of a muscle cell is termed the sarcoplasmic reticulum; and the cell membrane in a muscle cell is termed the sarcolemma. [9]
The rough endoplasmic reticulum is so named because the cytoplasmic surface is covered with ribosomes, giving it a bumpy appearance when viewed through an electron microscope. The smooth ER appears smooth since its cytoplasmic surface lacks ribosomes. [27]
translation and folding of new proteins (rough endoplasmic reticulum), expression of lipids (smooth endoplasmic reticulum) single-membrane compartment: all eukaryotes: rough endoplasmic reticulum is covered with ribosomes (which are bound to the ribosome membrane), has folds that are flat sacs; smooth endoplasmic reticulum has folds that are ...
Rough endoplasmic reticulum – A section of the endoplasmic reticulum on with the protein manufacturing organelle i.e. ribosomes are attached is termed as rough endoplasmic reticulum which give it a "rough" appearance (hence its name). [6] Its primary function is the synthesis of enzymes and other proteins.
Rough (containing ribosomes) and smooth (without ribosomes) microsomes are made from the endoplasmic reticulum through cell disruption. These microsomes have an inside that is exactly the same as the endoplasmic reticulum lumen. Both forms of microsomes can be purified by a process known as equilibrium density centrifugation. Rough and smooth ...
Organelles (literally "little organs") are usually membrane-bound structures inside the cell that have specific functions. Some major organelles that are suspended in the cytosol are the mitochondria, the endoplasmic reticulum, the Golgi apparatus, vacuoles, lysosomes, and in plant cells, chloroplasts.
Synthesis of proteins is by the rough endoplasmic reticulum (RER), and both the rough and smooth endoplasmic reticulum (SER) are involved in secretion of the proteins formed. [citation needed] The endoplasmic reticulum (ER) is involved in conjugation of proteins to lipid and carbohydrate moieties synthesized by, or modified within, the hepatocytes.