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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
Clinical trials suggest that it is more effective than other 5-HT 3 antagonists in preventing delayed CINV (nausea and vomiting that occur more than 24 hours after the first dose of chemotherapy). [15] It is taken once daily. Dolasetron was first mentioned in the literature in 1989. [16]
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated. [1] [2]
“Zofran is an anti-nausea medication,” says Qing, and it’s typically used preventatively. Zofran is an antiemetic that works by blocking the chemical that causes nausea and vomiting, per the ...
Nausea can be caused by weight loss drugs, pregnancy, food poisoning, migraines. Doctors share home remedies for nausea, including ginger and peppermint.
These drugs block one or more of the nerve signals that cause nausea and vomiting. During the first 24 hours after chemotherapy, the most effective approach appears to be blocking the 5-HT 3 nerve signal. [10] Approved 5-HT 3 inhibitors include dolasetron (Anzemet), granisetron (Kytril, Sancuso), and ondansetron (Zofran). Their antiemetic ...
If you’ve been experiencing nausea, for example, they may prescribe an anti-nausea drug. Or they might recommend over-the-counter (OTC) meds to help treat symptoms like gas, bloating, and diarrhea.
They are efficacious in treating chemotherapy-induced emesis and postoperative nausea and vomiting. [1] They include, but are not limited to: Dolasetron; Granisetron; Ondansetron; Palonosetron; Tropisetron; Other 5-HT 3 antagonists have been considered for use in the treatment of irritable bowel syndrome: Alosetron; Cilansetron