Search results
Results From The WOW.Com Content Network
Paradoxical disinhibition is a paradoxical reaction, an uncommon but recognized phenomenon, characterized by acute excitement and an altered mental state, caused by benzodiazepines. The mechanism is poorly known, but the most accepted theory is that it occurs secondary to inhibition of the restraining influences of the cortex and frontal lobe ...
A paradoxical reaction (or paradoxical effect) is an effect of a chemical substance, such as a medical drug, that is opposite to what would usually be expected. An example of a paradoxical reaction is pain caused by a pain relief medication .
Paradoxical behavior is often not recalled by the patient due to the amnesia-producing properties of the drug. In extreme situations, flumazenil can be administered to inhibit or reverse the effects of midazolam. Antipsychotic medications, such as haloperidol, have also been used for this purpose. [47] Midazolam is known to cause respiratory ...
Paradoxical reactions are rare in the general population, with an incidence rate below 1% and similar to placebo. [ 8 ] [ 120 ] However, they occur with greater frequency in recreational abusers, individuals with borderline personality disorder , children, and patients on high-dosage regimes.
The first one was Extra Credits: Firefall, which spanned 5 episodes and was requested by Red 5 Studios to help reinforce the game design decisions in their video game Firefall. [34] After moving to YouTube, the team decided to make use of their space to expand their channel with new series running on different days of the week.
Others must be bioactivated into a toxic compound that will in turn bind to proteins. The second criterion of cellular damage can come either from a toxic drug/drug metabolite, or from an injury or infection. These will sensitize the immune system to the drug and cause a response. Idiosyncratic reactions fall conventionally under toxicology.
Bradley Lamar Colburn (born February 10, 1987), [3] better known by his online alias theRadBrad, is an American YouTuber and Let's Player most notable for his video game walkthroughs of various new games. [4] [5] [6] He has been interviewed by various publications since becoming active in 2010.
People Make Games (PMG) is a British investigative video game journalism YouTube channel. The channel focuses on the developers and people who make video games . People Make Games has reported on topics such as video game crunch , [ 2 ] [ 3 ] outsourcing , [ 4 ] and worker exploitation .