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Medroxyprogesterone acetate (MPA), also known as depot medroxyprogesterone acetate (DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. [10] [4] It is used as a method of birth control and as a part of menopausal hormone therapy.
Medroxyprogesterone acetate (brand names Depo-Provera, ... As will all birth control medications, certain side effects may occur from taking the hormonal supplements.
Estradiol cypionate/medroxyprogesterone acetate (EC/MPA), sold under the brand name Cyclofem among others, is a form of combined injectable birth control. [2] It contains estradiol cypionate (EC), an estrogen, and medroxyprogesterone acetate (MPA), a progestin. [2] It is recommended for short-term use and is given once a month by injection into ...
It found that prolonged medroxyprogesterone acetate use may be associated with an increased risk of developing a type of slow-growing (and usually benign) tumor in the membranes around the brain ...
Examples of progestogens include natural or bioidentical progesterone as well as progestins such as medroxyprogesterone acetate and norethisterone. [1] Side effects of progestogens include menstrual irregularities, headaches, nausea, breast tenderness, mood changes, acne, increased hair growth, and changes in liver protein production among others.
Medroxyprogesterone, also known as 6α-methyl-17α-hydroxyprogesterone or as 6α-methyl-17α-hydroxypregn-4-en-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone. [ 2 ] [ 3 ] It is specifically a derivative of 17α-hydroxyprogesterone with a methyl group at the C6α position.
[14] [130] Medroxyprogesterone acetate has similar side effects and risks as cyproterone acetate, but is not associated with liver problems. [ 131 ] [ 104 ] Numerous other progestogens and by extension antigonadotropins have been used to suppress testosterone levels in men and are likely useful for such purposes in transgender women as well.
Conversely, progesterone can still produce side effects related to its antimineralocorticoid and neurosteroid activity. [20] Compared to the progestin medroxyprogesterone acetate, there are fewer reports of breast tenderness with progesterone. [28]