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Human ova grow from primitive germ cells that are embedded in the substance of the ovaries. [10] The ovum is one of the largest cells in the human body, typically visible to the naked eye without the aid of a microscope or other magnification device. [11] The human ovum measures approximately 120 μm (0.0047 in) in diameter. [12]
An oocyte (/ ˈ oʊ ə s aɪ t /, oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in a female fetus in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis ...
Human ovum examined fresh in the follicular fluid. The zona pellucida is seen as a thick clear girdle surrounded by the cells of the corona radiata. The egg itself shows a central granular deutoplasmic area and a peripheral clear layer, and encloses the germinal vesicle, in which is seen the germinal spot.
The zona pellucida is a translucent matrix of cross-linked glycoprotein filaments that surrounds the mammalian oocyte and is 6.5–20 μm thick depending on the species. Its formation, which depends on a conserved zona pellucida-like (ZP) module that mediates the polymerization of egg coat components, [2] is critical to successful fertilization. [3]
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries.It secretes hormones that influence stages of the menstrual cycle.In humans, women have approximately 200,000 to 300,000 follicles at the time of puberty, [1] [2] each with the potential to release an egg cell (ovum) at ovulation for fertilization. [3]
In fact, a primary oocyte is, by its biological definition, a cell whose primary function is to divide by the process of meiosis. [16] However, although this process begins at prenatal age, it stops at prophase I. In late fetal life, all oocytes, still primary oocytes, have halted at this stage of development, called the dictyate.
The process of ovulation and gamete production, oogenesis, in a human ovary. The ovaries are the site of production and periodical release of egg cells, the female gametes. In the ovaries, the developing egg cells (or oocytes) mature in the fluid-filled follicles. Typically, only one oocyte develops at a time, but others can also mature ...
The late tertiary or pre-ovulatory follicle ruptures and discharges the oocyte (that has become a secondary oocyte), ending folliculogenesis. Follicle ‘selection’ is the process by which a single ‘dominant’ follicle is chosen from the recruited cohort or wave for preferential growth.