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  2. Infectious canine hepatitis - Wikipedia

    en.wikipedia.org/wiki/Infectious_canine_hepatitis

    Most dogs recover spontaneously without treatment. Prevention is through vaccination (ATCvet code QI07AA05 and various combination vaccines). Most combination vaccines for dogs contain a modified canine adenovirus type-2. [4] CAV-2 is one of the causes of respiratory infections in dogs, but it is similar enough to CAV-1 that vaccine for one ...

  3. Hyperbilirubinemia in adults - Wikipedia

    en.wikipedia.org/wiki/Hyperbilirubinemia_in_adults

    Extremely high levels of unconjugated bilirubin in plasma enables bilirubin to cross the blood-brain-barrier to reach the brain and central nervous system to impart damage. This is termed kernicterus, or bilirubin encephalopathy. Kernicterus is rare in adults but is prevalent in newborns with underdeveloped blood-brain barriers and lower ...

  4. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    When the total serum bilirubin increases over 95th percentile for age during the first week of life for high risk babies, it is known as hyperbilirubinemia of the newborn (neonatal jaundice) and requires light therapy to reduce the amount of bilirubin in the blood. Pathological jaundice in newborns should be suspected when the serum bilirubin ...

  5. Child–Pugh score - Wikipedia

    en.wikipedia.org/wiki/Child–Pugh_score

    In primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC), some use a modified Child–Pugh score where the bilirubin references are changed to reflect the fact that these diseases feature high conjugated bilirubin levels. The upper limit for 1 point is 68 μmol/L (4 mg/dL) and the upper limit for 2 points is 170 μmol/L (10 ...

  6. Bilirubin - Wikipedia

    en.wikipedia.org/wiki/Bilirubin

    Bilirubin (BR) (from the Latin for "red bile") is a red-orange compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates.This catabolism is a necessary process in the body's clearance of waste products that arise from the destruction of aged or abnormal red blood cells. [3]

  7. Jaundice - Wikipedia

    en.wikipedia.org/wiki/Jaundice

    Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels. [3] [6] Jaundice in adults is typically a sign indicating the presence of underlying diseases involving abnormal heme metabolism, liver dysfunction, or biliary-tract obstruction. [7]

  8. Gilbert's syndrome - Wikipedia

    en.wikipedia.org/wiki/Gilbert's_syndrome

    People with GS predominantly have elevated unconjugated bilirubin, while conjugated bilirubin is usually within the normal range or is less than 20% of the total. Levels of bilirubin in GS patients are reported to be from 20 μM to 90 μM (1.2 to 5.3 mg/dl) [ 38 ] compared to the normal amount of < 20 μM.

  9. Model for End-Stage Liver Disease - Wikipedia

    en.wikipedia.org/wiki/Model_for_End-Stage_Liver...

    The Model for End-Stage Liver Disease, or MELD, is a scoring system for assessing the severity of chronic liver disease.It was initially developed to predict mortality within three months of surgery in patients who had undergone a transjugular intrahepatic portosystemic shunt (TIPS) procedure, [1] and was subsequently found to be useful in determining prognosis and prioritizing for receipt of ...