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Mometasone/formoterol, sold under the brand name Dulera among others, is a fixed-dose combination medication used in the long-term treatment of asthma. [1] It contains mometasone a steroid and formoterol a long-acting beta agonist. [1] It is only recommended in those for whom an inhaled steroid is not sufficient. [1] It is used by inhalation. [1]
It contains budesonide, a steroid; and formoterol, a long-acting β 2-agonist (LABA). [2] The product monograph does not support its use for sudden worsening or treatment of active bronchospasm. [2] However, a 2020 review of the literature does support such use. [6] It is used by breathing in the medication. [2]
Fluticasone, a corticosteroid, works by decreasing inflammation while salmeterol, a long-acting beta-adrenoceptor agonist (LABA), works by activating beta-2 adrenergic receptors. [5] The combination was approved for medical use in the United States in 2000. [5] A generic version was approved in the United States in 2019. [7]
When combined with inhaled steroids, β adrenoceptor agonists can improve symptoms. [1] [2] In children this benefit is uncertain and they may be potentially harmful. [2]They should not be used without an accompanying steroid due to an increased risk of severe symptoms, including exacerbation in both children and adults. [3]
In adults who have stable asthma while they are taking a combination of LABA and inhaled corticosteroids (ICS), stopping LABA may increase the risk of asthma exacerbations that require treatment with corticosteroids by mouth. [226] Stopping LABA probably makes little or no important difference to asthma control or asthma-related quality of life ...
[6] [7] The medications work in different ways: fluticasone furoate is an inhaled corticosteroid (ICS), umeclidinium is a long-acting muscarinic antagonist (LAMA), and vilanterol is a long-acting beta-agonist (LABA). In 2022, it was the 144th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [8] [9]
Laba congee or porridge (simplified Chinese: 腊八粥; traditional Chinese: 臘八粥; pinyin: làbā zhōu) is a Chinese ceremonial congee dish traditionally eaten on the eighth day of the twelfth month in the Chinese calendar. [1] The day on which it is traditionally eaten is commonly known as the Laba Festival. The earliest form of this ...
Adverse effects are mainly related to its antimuscarinic effects. Common adverse drug reactions (≥1% of people) include: dry mouth and/or throat irritation. Rarely (<0.1% of patients) treatment is associated with: urinary retention, constipation, acute angle closure glaucoma, palpitations (notably supraventricular tachycardia and atrial fibrillation) and allergy (rash, angioedema ...