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In the last decades, triazolopyrimidines and their metal complexes have been looked at as an alternative drug to the existing commercial antimonials, searching for a decrease in side effects and the development of parasite drug resistance. [13]
Anthelmintic resistance in parasites is widespread; drug resistance exists in all livestock hosts and to all anthelmintic drug classes. [13] This is a major threat to the sustainability of modern ruminant livestock production, resulting in reduced productivity, compromised animal health and welfare, [ 12 ] and increased greenhouse gas emissions ...
Benznidazole is an antiparasitic medication used in the treatment of Chagas disease. [2] While it is highly effective in early disease, the effectiveness decreases in those who have long-term infection. [3] It is the first-line treatment given its moderate side effects compared to nifurtimox. [1] It is taken by mouth. [2] Side effects are ...
Side effects include loss of appetite, nausea, abdominal pain, cough, feeling tired, muscle pain, irregular heartbeat, and kidney problems. [1] It should not be used in people with significant heart, liver, or kidney problems. [1] It is not recommended during breastfeeding. [1] It belongs to a group of medications known as the pentavalent ...
Ivermectin is an antiparasitic drug. [7] After its discovery in 1975, [8] its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. [9] Approved for human use in 1987, [10] it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.
Common side effects include nausea, a metallic taste, loss of appetite, and headaches. [10] Occasionally seizures or allergies to the medication may occur. [10] Some state that metronidazole should not be used in early pregnancy, while others state doses for trichomoniasis are safe.
An ectoparasiticide is an antiparasitic drug used in the treatment of ectoparasitic infestations. [1] These drugs are used to kill the parasites that live on the body surface. Permethrin , sulfur , lindane , dicophane , benzyl benzoate , ivermectin and crotamiton are well known ectoparasiticides. [ 2 ]
Serious side effects include problems with vision, muscle damage, seizures, and low blood cell levels. [ 1 ] [ 4 ] Chloroquine is a member of the drug class 4-aminoquinoline . [ 1 ] As an antimalarial, it works against the asexual form of the malaria parasite in the stage of its life cycle within the red blood cell . [ 1 ]