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The cellular spindle apparatus includes the spindle microtubules, associated proteins, which include kinesin and dynein molecular motors, condensed chromosomes, and any centrosomes or asters that may be present at the spindle poles depending on the cell type. [4] The spindle apparatus is vaguely ellipsoid in cross
The actual set of genes essential for kinetochore function varies from one species to another. [7] [8] Kinetochore functions include anchoring of chromosomes to MTs in the spindle, verification of anchoring, activation of the spindle checkpoint and participation in the generation of force to propel chromosome movement during cell division. [9]
The function of the gamma motor neurons is not to supplement the force of muscle contraction provided by the extrafusal fibers, but to modify the sensitivity of the muscle spindle sensory afferents to stretch.
A muscle spindle, with γ motor and Ia sensory fibers. A type Ia sensory fiber, or a primary afferent fiber, is a type of afferent nerve fiber. [1] It is the sensory fiber of a stretch receptor called the muscle spindle found in muscles, which constantly monitors the rate at which a muscle stretch changes.
Intrafusal muscle fibers are skeletal muscle fibers that serve as specialized sensory organs (proprioceptors). [ 1 ] [ 2 ] They detect the amount and rate of change in length of a muscle . [ 1 ] They constitute the muscle spindle , [ 2 ] and are innervated by both sensory (afferent) and motor (efferent) fibers.
The function of astral microtubules can be generally considered as determination of cell geometry. They are absolutely required for correct positioning and orientation of the mitotic spindle apparatus , and are thus involved in determining the cell division site based on the geometry and polarity of the cells.
An acentric chromosome is fragment of a chromosome that lacks a centromere. Since centromeres are the attachment point for spindle fibers in cell division, acentric fragments are not evenly distributed to daughter cells during cell division. As a result, a daughter cell will lack the acentric fragment and deleterious consequences could occur.
The function of the reflex is generally thought to be maintaining the muscle at a constant length but the response is ... the extrafusal fibers of the muscle spindle.