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Combining metformin with gliflozins may further reduce risk As diabetes prevalence increases, more people may face higher risks of developing neurodegenerative conditions as they grow older.
Not only that, they had a 52 percent lower risk of vascular dementia, and a 39 percent lower risk of Alzheimer’s dementia. People who took SGLT-2 inhibitors for longer periods of time seemed to ...
A diabetes drug may help prevent dementia, new research shows. Tim Newman. September 2, 2024 at 6:30 AM. SGLT-2 inhibitors have been linked with a 35% lower dementia risk in a recent study.
Metformin inhibits cyclic AMP production, blocking the action of glucagon, and thereby reducing fasting glucose levels. [117] Metformin also induces a profound shift in the faecal microbial community profile in diabetic mice, and this may contribute to its mode of action possibly through an effect on glucagon-like peptide-1 secretion. [108]
LATE is a term that describes a prevalent medical condition with impaired memory and thinking in advanced age, often culminating in the dementia clinical syndrome. [1] In other words, the symptoms of LATE are similar to those of Alzheimer's disease. The acronym LATE stands for Limbic-predominant Age-related TDP-43 Encephalopathy.
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