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Diverticular disease is when problems occur due to diverticulosis, a benign condition defined by the formation of pouches (diverticula) from weak spots in the wall of the large intestine. [1] This disease spectrum includes diverticulitis , symptomatic uncomplicated diverticular disease (SUDD), and segmental colitis associated with ...
Several factors may influence the development of the disease, such as local colonic ischemia, fecal stasis, or mucosal prolapse. SCAD shares some features with inflammatory bowel disease, including the increase of tumor necrosis factor (TNF) alpha during active disease, and decrease in TNF during health improvement. The pathogenesis of SCAD ...
A 2011 review found that a high-fiber diet may prevent diverticular disease, and found no evidence for the superiority of low-fiber diets in treating diverticular disease. [33] A 2011 long-term study found that a vegetarian diet and high fiber intake were both associated with lower risks of hospital admission or death from diverticulitis. [34]
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Diverticulitis is defined as diverticular disease with signs and symptoms of diverticular inflammation. Clinical features of acute diverticulitis include constant abdominal pain, localized abdominal tenderness in the left lower quadrant of the abdomen, nausea, vomiting, constipation or diarrhea, fever and leukocytosis .
Every so often, an acute resurgence of the original symptoms may appear; this is known as a "flare-up". Depending on the circumstances, it may go away on its own or require medication. The time between flare-ups may be anywhere from weeks to years, and varies wildly between patients – a few have never experienced a flare-up. [120]