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Dense irregular connective tissue also makes up submucosa of the digestive tract, lymph nodes, and some types of fascia. [5] Other examples include periosteum and perichondrium of bones, and the tunica albuginea of testis. In the submucosa layer, the fiber bundles course in varying planes allowing the organ to resist excessive stretching and ...
In the papillary dermis, there is occasionally focal, mild hemorrhage as well as slight vascular dilatation. [15] A characteristic of reticular erythematous mucinosis is the separation of dermal collagen bundles, and the upper and mid dermis are the primary areas where variable amounts of basophilic mucin are visible. [3]
There is a biphasic pattern in the early stages: in the papillary dermis, the vascular spaces are dilated and slit-like, resembling lymphatic vessels, which are concentrated around sweat glands and frequently form small hemangiomatous nodules, dissecting the collagen bundles. In the deep dermis, the vascular spaces are angulated and slit-like ...
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
Wedge-shaped hypergranulosis can occur in the eccrine ducts (acrosyringia) or hair follicles (acrotrichia). In the hypertrophic subtype, the associated hyperkeratosis, parakeratosis, hypergranulosis, papillomatosis, acanthosis, and hyperplasia markedly increased with thicker collagen bundles forming in the dermis.
Dense connective tissue, also called dense fibrous tissue, is a type of connective tissue with fibers as its main matrix element. [1] The fibers are mainly composed of type I collagen . Crowded between the collagen fibers are rows of fibroblasts , fiber-forming cells, that generate the fibers.