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The lateral spinothalamic tract (or lateral spinothalamic fasciculus), is a bundle of afferent nerve fibers ascending through the white matter of the spinal cord, in the spinothalamic tract, carrying sensory information to the brain. It carries pain, and temperature sensory information (protopathic sensation) to the thalamus.
The second-order neurons ascend to the brain stem and thalamus in the ventrolateral, or anterolateral, quadrant of the contralateral half of the spinal cord, forming the spinothalamic tract. [1] The spinothalamic tract is the main pathway associated with pain and temperature perception, which immediately crosses the spinal cord laterally. [1]
The spinohypothalamic tract or spinohypothalamic fibers is a sensory fiber tract projecting from the spinal cord to the hypothalamus directly to mediate reflex autonomic and endocrine responses to painful stimuli (the hypothalamus receives additional indirect nociceptive projections from the reticular formation (see: spinoreticular tract), and periaqueductal gray (see: spinomesencephalic tract).
Its fibres are carried in the spinothalamic tract, unlike the fine touch, which is carried in the dorsal column. [ 23 ] As fine touch normally works in parallel to crude touch, a person will be able to localize touch until fibres carrying fine touch (in the dorsal column–medial lemniscus pathway) have been disrupted.
The spinothalamic tract is a sensory pathway originating in the spinal cord. It transmits information to the thalamus about pain, temperature, itch and crude touch . There are two main parts: the lateral spinothalamic tract , which transmits pain and temperature, and the anterior (or ventral) spinothalamic tract , which transmits crude touch ...
The main supply of blood to the brainstem is provided by the basilar arteries and the vertebral arteries. [14]: 740 It is important to note that there is a bit of variability in how these arteries connect and supply blood to the brain, such as where the arteries fuse or are reinforced. The variability that exists allows for syndromes to be ...
The substantia gelatinosa is one point (the nucleus proprius being the other) where first order neurons of the spinothalamic tract synapse. Many μ and κ-opioid receptors, presynaptic and postsynaptic, are found on these nerve cells; they can be targeted to manage pain of distal origin. For instance, neuraxial administration of opioids results ...
The dorsal column–medial lemniscus pathway (DCML) (also known as the posterior column-medial lemniscus pathway (PCML) is the major sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (body position) from the skin and joints.