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Mycoplasma pneumoniae is one of the smallest free-living organisms and a common bacterial respiratory tract pathogen. Upper respiratory tract infections and acute bronchitis are the most common manifestations of M. pneumoniae infection, but pneumonia can also occur.
Most Mycoplasma pneumoniae infections are self-limiting. Healthcare providers routinely treat pneumonia caused by M. pneumoniae with antibiotics. Some strains of M. pneumoniae may be resistant to macrolides.
Most patients with M pneumoniae pneumonia present in outpatient settings, and treatment is often with empiric antibiotics for atypical pneumonia. Note that many patients may undergo a period of symptomatic management before seeking medical attention and/or receiving antibiotic treatment.
Healthcare providers can use several types of antibiotics to treat people with pneumonia caused by M. pneumoniae. Some M. pneumoniae are resistant to some antibiotics used for treatment. CDC has information on the potential danger of antibiotic resistance and how to prevent it.
In the treatment of mycoplasmal pneumonia, antimicrobials against M pneumoniae are bacteriostatic, not bactericidal. Tetracycline and erythromycin compounds are very effective. The...
Mycoplasma pneumoniae are a common cause of bacterial respiratory infections. These bacteria have unique features that impact treatment options and pathogenesis. M. pneumoniae infections are most common in young adults and school-age children.
Antibiotics, particularly oral erythromycin, azithromycin, and clarithromycin, commonly are used for treating mycoplasmal respiratory tract infections, with tetracycline also showing...
A macrolide or tetracycline antibiotic is usually effective as first-line treatment of mycoplasma infections in both uncomplicated and more severe community-acquired pneumonia. Fluoroquinolones may be effective as second-line treatment if previous antibiotics fail.
Mycoplasma pneumoniae commonly causes "atypical pneumonia" a name derived because of its lack of response to antibiotics. Mycoplasma pneumoniae is the most widely studied Mycoplasma species due to its increasing prevalence.
Mycoplasma pneumoniae infection occurs in outbreaks approximately every 4 years. Erythromycin is preferred if a macrolide is needed in pregnancy, for example, if there is true penicillin allergy and the benefits of antibiotic treatment outweigh the harms.