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  2. Xenohormone - Wikipedia

    en.wikipedia.org/wiki/Xenohormone

    There has been difficult comprehensive research on the specific outcomes on the relationship of xenohormone exposure and its effect on the health of humans. There have also been research on ways to mitigate the risk and its threats to public health like the development of a biomarker to identify and measure the level of xenohormones in blood to ...

  3. Xenoestrogen - Wikipedia

    en.wikipedia.org/wiki/Xenoestrogen

    Xenoestrogens are a type of xenohormone that imitates estrogen.They can be either synthetic or natural chemical compounds.Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any ...

  4. Off-target activity - Wikipedia

    en.wikipedia.org/wiki/Off-target_activity

    An example of this is the repurposing of the antimineralocorticoid and diuretic spironolactone, which was found to produce feminization and gynecomastia as side effects, for use as an antiandrogen in the treatment of androgen-dependent conditions like acne and hirsutism in women. [1] Metformin also causes off-target activity. [citation needed]

  5. AstraZeneca to build $1.5-billion cancer drug plant in Singapore

    www.aol.com/news/astrazeneca-plans-build-1-5...

    (Reuters) -AstraZeneca plans to build a $1.5 billion manufacturing facility in Singapore to produce a promising category of cancer-killing drugs called antibody-drug conjugates (ADCs), the Anglo ...

  6. Hormone - Wikipedia

    en.wikipedia.org/wiki/Hormone

    Hormone effects can be inhibited, thus regulated, by competing ligands that bind to the same target receptor as the hormone in question. When a competing ligand is bound to the receptor site, the hormone is unable to bind to that site and is unable to elicit a response from the target cell.

  7. Target is sued for defrauding shareholders about DEI

    www.aol.com/news/target-sued-defrauding...

    Target has been sued for allegedly concealing the risks of its diversity and social initiatives, leading to a backlash that caused customers to flee and the stock price of the Minneapolis-based ...

  8. Metonitazene - Wikipedia

    en.wikipedia.org/wiki/Metonitazene

    Metonitazene is an analgesic compound related to etonitazene, [2] [3] which was first reported in 1957, [4] and has been shown to have approximately 1000 times the potency of morphine by central routes of administration, [5] but if used orally it has been shown to have approximately 10 times the potency of morphine.

  9. Novartis Institute for Tropical Diseases - Wikipedia

    en.wikipedia.org/wiki/Novartis_Institute_for...

    NITD was founded in 2002 as a public-private partnership between Swiss-based pharmaceutical company Novartis and the Singapore Economic Development Board. [1]NITD states its goals are "to discover novel treatments and prevention methods for major tropical diseases."