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Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...
In the EPC trial, in which bicalutamide monotherapy (150 mg/day) was evaluated for treatment of early prostate cancer in 8,113 men, the incidence of abnormal liver function tests at 3-year median follow-up was 3.4% for bicalutamide plus standard care (n=4,052) and 1.9% for standard care alone (n=4,061).
Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer. [10] It is typically used together with a gonadotropin-releasing hormone (GnRH) analogue or surgical removal of the testicles to treat metastatic prostate cancer (mPC).
For cancer treatment, it is given intravenously in combination with fluorouracil, leucovorin, and irinotecan. [ 15 ] In July 2014, aflibercept (Eylea) was approved for the treatment of people with visual impairment due to diabetic macular edema [ 22 ] In May 2019, the US FDA expanded the indication for aflibercept to include all stages of ...
John L.S. Grant, who joined Glenfarclas in 1973, is the current chairman. The company was named Distiller of the Year by Whisky Magazine in 2006, 2020 and 2023 . [3] Since 2006 Glenfarclas has been distributed in the UK by Pol Roger Ltd. [4] In 2008 the company began sponsoring horseracing with the Glenfarclas Cross Country Handicap Chase at
Ballindalloch (Scottish Gaelic: Baile na Dalach) is a small village on the River Spey in Scotland. It is known for its whisky distilleries and for Ballindalloch Castle. [1] [2] Until 1961 there was a station on the Great North of Scotland Railway. In Ballindalloch itself, there are two distilleries, Cragganmore distillery and Ballindalloch ...
Enzalutamide, sold under the brand name Xtandi, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer. [2] [9] It is indicated for use in conjunction with castration in the treatment of metastatic castration-resistant prostate cancer (mCRPC), [2] nonmetastatic castration-resistant prostate cancer, [2] and metastatic castration-sensitive prostate ...
In 1923, after Gordon death, his widow Mary Jane takes over and finally sells it to the Cragganmore-Glenlivet Distillery Co., which is owned equally by Peter Mackie from White Horse and Ballindalloch Estate. [3] Mackie sold his share to The Distillers Company but Macpherson-Grant family keeps its 50% ownership until 1965. [4]