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Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2) are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
Supplements are not recommended for prevention of cancer as any effects of cholecalciferol are very small. [35] Although correlations exist between low levels of blood serum cholecalciferol and higher rates of various cancers, multiple sclerosis , tuberculosis , heart disease, and diabetes, [ 36 ] the consensus is that supplementing levels is ...
The active vitamin D metabolite, calcitriol, exerts its biological effects by binding to the vitamin D receptor (VDR), which is primarily located in the nuclei of target cells. [ 1 ] [ 13 ] When calcitriol binds to the VDR, it enables the receptor to act as a transcription factor , modulating the gene expression of transport proteins involved ...
There's lots of confusion around the difference between vitamin D2 and vitamin D3, and which is best for whom. Doctors and experts explain.
The two most common forms are vitamin D2 and vitamin D3. Vitamin D is a fat-soluble vitamin which plays a major role in bone health, immunity, and nerve communication between the brain and muscle ...
Calcium/cholecalciferol is a combination of a calcium salt and vitamin D 3 (cholecalciferol). It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well for osteoporosis in combination with other medications. [1] [2]