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Scaffolds localize the signaling reaction to a specific area in the cell, a process that could be important for the local production of signaling intermediates. A particular example of this process is the scaffold, A-kinase anchor proteins (AKAPs), which target cyclic AMP-dependent protein kinase to various sites in the cell. [7]
This is an example of a scaffold. Scaffolding is a technique used in bioinformatics. It is defined as follows: [1] Link together a non-contiguous series of genomic sequences into a scaffold, consisting of sequences separated by gaps of known length. The sequences that are linked are typically contiguous sequences corresponding to read overlaps.
In computational biology, N50 and L50 are statistics of a set of contig or scaffold lengths. The N50 is similar to a mean or median of lengths, but has greater weight given to the longer contigs. It is used widely in genome assembly , especially in reference to contig lengths within a draft assembly.
Micro-mass cultures of C3H-10T1/2 cells at varied oxygen tensions stained with Alcian blue. A commonly applied definition of tissue engineering, as stated by Langer [3] and Vacanti, [4] is "an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve [Biological tissue] function or a ...
the description of scaffold-attachment elements (SARs) by Laemmli and coworkers, which were thought to demarcate the borders of a given chromatin domain [2] the characterization of matrix-associated regions (MARs) the first examples of which supported the immunoglobulin kapp-chain enhancer according to its occupancy with transcription factors [ 3 ]
Scaffolding for rehabilitation in Madrid, Spain [1] Scaffolding for renovation on the Virgin Mary statue, Santiago de Chile, Chile.. Scaffolding, also called scaffold or staging, [2] is a temporary structure used to support a work crew and materials to aid in the construction, maintenance and repair of buildings, bridges and all other human-made structures.
A contig (from contiguous) is a set of overlapping DNA segments that together represent a consensus region of DNA. [1] In bottom-up sequencing projects, a contig refers to overlapping sequence data (); [2] in top-down sequencing projects, contig refers to the overlapping clones that form a physical map of the genome that is used to guide sequencing and assembly. [3]
Scaffold (chemistry), the core structure of a compound or a class of compounds; Scaffold protein, a regulator of cell signalling pathways; Scaffold, a protein that is used as a starting point for the design of antibody mimetics; Tissue scaffold, in tissue engineering, an artificial structure capable of supporting three-dimensional tissue formation