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Diphenhydramine (as Benadryl) is not typically used to treat anxiety because its long-term use may cause adverse effects, such as memory loss, especially in the elderly. [40] Benadryl is not approved by the US Food and Drug Administration for treating anxiety. [ 40 ]
Benadryl Itch Stopping Cream is a topical cream used to provide temporary itch relief for allergies, hives or even some insect bites. It can be found in the United States and Canada. This topical medication contains 2% of diphenhydramine hydrochloride and 1% of zinc acetate. This medication is intended for topical use only and not to be ingested.
The recommended dosage of Benadryl tablets for adults is 1 to 2 tablets every 4 to 6 hours, [1] and only 1 tablet every 4 to 6 hours for children under the age of 12. [2]The Benadryl challenge is an internet challenge that emerged in 2020, revolving around the deliberate consumption, excessive use and overdose of the antihistamine medicine diphenhydramine (commonly sold in the United States ...
Multiple teens have been hospitalized after ingesting up to 14 Benadryl doses at once, inspired by a TikTok challenge aimed at hallucinating. Experts say the activity could be deadly.
Synthetic compounds such as diphenhydramine (Benadryl) and dimenhydrinate (Dramamine) are deliriants. Nutmeg, although purportedly not as strong or as unpleasant as diphenhydramine or scopolamine, is considered a deliriant, due to its propensity to cause anticholinergic-like symptoms when taken in large doses. [30]
This use of diphenhydramine has been criticized for a number of reasons, ranging from ethical to safety concerns, [25] but also due to the risk of diphenhydramine's paradoxical reaction, which induces hyperactivity and irritability. [26] This phenomenon can also be observed in adults who use the medication as a sleep aid.