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Belumosudil, sold under the brand name Rezurock among others, is a medication used for the treatment of chronic graft versus host disease (cGvHD). [1] [5] [6] It is in the class of drugs known as serine/threonine kinase inhibitors. [6] Specifically, it is an inhibitor of Rho-associated coiled-coil kinase 2 (ROCK2; ROCK-II). [7]
Disufenton sodium has been researched as a potential treatment for use in brain tumors and cancers, including diffuse intrinsic pontine glioma (DIPG) [7] [8] and glioblastoma. [9] [10] A compound (NHPN-1010) containing a combination of disufenton sodium and acetylcysteine has been researched as a potential treatment for tinnitus and hearing loss.
In particular, quinoline-type drugs are known to be ototoxic. Examples include chloroquine and hydroxychloroquine which are quinine-like. Apart from antimalarial effects, these drugs are also used in the treatment of other diseases such as dermatological, immunological, rheumatological, and severe infectious diseases. [25]
Credit - Getty Images. 2023 was a strong year for innovative new drugs, with new medications for Alzheimer’s disease, weight loss, and the first treatment based on the gene-editing technology ...
Neuromonics is a patented treatment for tinnitus that combines acoustic stimulation with cognitive-behavioural therapy to provide relief for people suffering from tinnitus. The treatment aims to retrain the brain to filter out the sounds of tinnitus, making them less noticeable and bothersome. The treatment was developed by audiologist Dr. Paul ...
The best-supported treatment for tinnitus is cognitive behavioral therapy (CBT). [5] [84] [102] It decreases the stress those with tinnitus feel. [103] This appears to be independent of any effect on depression or anxiety. [102] Acceptance and commitment therapy (ACT) also shows promise in the treatment of tinnitus. [104] Relaxation techniques ...