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As of July 2020, the segment from the exit with U.S. Route 74 to the current interchange of NC 226 (Polkville Road) has been open and further extensions of the route will be coming soon. The segment from NC 226 (Polkville Road) to NC 150 (Cherryville Road) is already on construction and will be subject to open to traffic in 2022.
The road heads due west around suburban developments, having interchanges at NC 50 (exit 39), Old Stage Road (exit 43), US 401 (exit 45), Bells Lake Road (exit 47), and Holly Springs Road (exit 50). The road eventually reaches NC 55 (exit 54) just south of Apex, where it becomes the Western Wake Expressway.
US 15/US 501 turns left in Durham. From the South Carolina state line, US 15 is in concurrency with US 401 to Laurinburg.Merging with US 501, it becomes what is known as "15-501" ("Fifteen Five-o-one"), a concurrency that extends for 106 miles (171 km) across central North Carolina; US 15 also the dominant partner, using its milemarkers along the route.
North Carolina Highway 308 Truck (NC 308 Truck) is a 2.5-mile (4.0 km) route that bypasses southeast of downtown Windsor. It overlaps at first with US 13 and US 17 , then with US 17 Business . The entire route is in Windsor , Bertie County .
In 1916 the North Carolina State Highway Commission prepared a map for the Five Year Federal Aid Program. The general present-day routing of US 70 was a mix of both improved and unimproved highways. When the highways were signed, the majority of US 70's routing ran along NC 10 which was built from the Georgia state line south of Murphy to Beaufort.
In the U.S. state of North Carolina, US 220 travels 123.4 miles (198.6 km) from an intersection with US 1 in Rockingham to the Virginia state line near Price, North Carolina. The highway is an important north–south route in Central North Carolina, connecting Rockingham, Asheboro, Greensboro, and Summerfield.
North Carolina Highway 691 (NC 691) was established in 1925 as a new primary routing between NC 69, in Ingalls, to NC 194, near Linville Falls. In 1926, NC 691 was truncated further north from Linville Falls, at the east end of Three Mile Highway; the old alignment replaced by NC 194.
North Carolina Highway 54 (NC 54) is a 55.0-mile-long (88.5 km) primary state highway in the U.S. state of North Carolina. The highway serves the Research Triangle area, between Burlington and Raleigh , connecting the cities and towns of Chapel Hill , Durham , Morrisville and Cary .