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MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is an organic compound. It is classified as a tetrahydropyridine . It is of interest as a precursor to the monoaminergic neurotoxin MPP + , which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain .
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes permanent symptoms of Parkinson's disease. (–)-Mitragynine is a naturally occurring tetrahydropyridine. 2,3,4,5-Tetrahydropyridine, a colorless liquid, is commercially available. It is an imine. Illustrating another isomer of tetrahydropyridine, 6-acetyl-2,3,4,5-tetrahydropyridine occurs ...
2′-NH 2-MPTP, also known as 2′-amino-MPTP, is a monoaminergic neurotoxin that was derived from MPTP and is used in scientific research to lesion brain monoaminergic systems in animals.
Buspirone appears to be relatively benign in cases of single-drug overdose, although no definitive data on this subject appear to be available. [31] In one clinical trial , buspirone was administered to healthy male volunteers at a dosage of 375 mg/day, and produced side effects including nausea , vomiting , dizziness , drowsiness , miosis ...
Arecoline is the primary active ingredient responsible for the central nervous system effects of the areca nut. Arecoline has been compared to nicotine; however, nicotine agonizes nicotinic acetylcholine receptors, whereas arecoline is primarily a partial agonist of muscarinic acetylcholine receptors, [4] [5] leading to its parasympathetic effects.
Mexico announced Monday the seizure of 440 pounds of methamphetamine in a cartel heartland, as it comes under mounting pressure from President Trump to tackle drug trafficking. The discovery was ...
Tetrahydropyridine; V. VU6067416; X. Xaliproden; Xanomeline; Xanomeline/trospium chloride This page was last edited on 16 July 2021, at 16:50 (UTC). Text is available ...
Lexapro, which contains the active ingredient escitalopram, is an antidepressant that belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs). It’s available as a ...