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Heinrich Hermann Robert Koch (/ k ɒ x / KOKH; [1] [2] German: [ˈʁoːbɛʁt ˈkɔx] ⓘ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist.As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he is regarded as one of the main founders of modern bacteriology.
Koch went on to study the mechanisms of other diseases and won the 1905 Nobel Prize in Physiology or Medicine for his discovery of the bacterium causing tuberculosis. [ 82 ] Although Koch arguably made the greatest theoretical contribution to understanding anthrax, other researchers were more concerned with the practical questions of how to ...
In September 2001, letters containing anthrax spores were mailed to several news media offices and two U.S. Senators, killing five people and infecting 17 others. Of those infected, 11 developed cutaneous anthrax, while 11 developed inhalation anthrax. 20 of the 22 infected worked at a site where contaminated mail was handled or received. [7]
Koch took his research into a new direction—applied research—to develop a tuberculosis treatment and use the profits to found his own research institute, autonomous from government. [17] In 1890 Koch introduced the intended drug, tuberculin, but it soon proved ineffective, and accounts of deaths followed in news press. [18]
1868 – Busch discovered that a sarcoma patient being surgically intervened to remove the tumor, after being exposed to a patient suffering from erysipelas, got a skin infection and her tumor disappeared. He inoculated some other cancer patients with many successes. [7] [4] 1876 – Demonstration that microbes can cause disease-anthrax (Robert ...
Koch's postulates (/ k ɒ x / KOKH) [2] are four criteria designed to establish a causal relationship between a microbe and a disease. The postulates were formulated by Robert Koch and Friedrich Loeffler in 1884, based on earlier concepts described by Jakob Henle , and the statements were refined and published by Koch in 1890. [ 3 ]
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In 1876, German biologist Robert Koch discovered that a bacterium (Bacillus anthracis) was the causative pathogen of anthrax, which became the first demonstration that a specific bacterium caused a specific disease and the first direct evidence of germ theory of diseases.