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Left untreated, the cats usually die from severe malnutrition or complications from liver failure. Treatment usually involves aggressive feeding through one of several methods. Cats can have a feeding tube inserted by a veterinarian so that the owner can feed the cat a liquid diet several times a day. If the cat stops vomiting and regains its ...
Cats with miliary dermatitis have a rash consisting of fine papules surmounted by small crusts. Although most are unaffected by rash, where noticed a broad rash can be concentrated to the back of the neck, scapular (shoulder blade) and surrounding areas, and/or the lower abdomen and surrounding areas.
An important infectious skin disease of cats is ringworm, or dermatophytosis.Other cat skin infections include parasitic diseases like mange and lice infestations.. Other ectoparasites, including fleas and ticks, are not considered directly contagious but are acquired from an environment where other infested hosts have established the parasite's life cycle.
Cholestatic pruritus is the sensation of itch due to nearly any liver disease, but the most commonly associated entities are primary biliary cholangitis, primary sclerosing cholangitis, obstructive choledocholithiasis, carcinoma of the bile duct, cholestasis (also see drug-induced pruritus), and chronic hepatitis C viral infection and other forms of viral hepatitis.
Rotor type hyperbilirubinemia is a distinct yet similar disorder to Dubin–Johnson syndrome [1] – both diseases cause an increase in conjugated bilirubin, but Rotor syndrome differs in that it is a result of impaired hepatocellular storage of conjugated bilirubin that leaks into plasma causing hyperbilirubinemia.
Because bilirubin is a skin irritant, jaundice is commonly associated with severe itchiness. [16] [17] Eye conjunctiva has a particularly high affinity for bilirubin deposition due to high elastin content. Slight increases in serum bilirubin can, therefore, be detected early on by observing the yellowing of sclerae.
Extremely high levels of unconjugated bilirubin in plasma enables bilirubin to cross the blood-brain-barrier to reach the brain and central nervous system to impart damage. This is termed kernicterus, or bilirubin encephalopathy. Kernicterus is rare in adults but is prevalent in newborns with underdeveloped blood-brain barriers and lower ...
Gilbert syndrome is a phenotypic effect, mostly associated with increased blood bilirubin levels, but also sometimes characterized by mild jaundice due to increased unconjugated bilirubin, that arises from several different genotypic variants of the gene for the enzyme responsible for changing bilirubin to the conjugated form.