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Encephalitis lethargica is an atypical form of encephalitis.Also known as "sleeping sickness" or "sleepy sickness" (distinct from tsetse fly–transmitted sleeping sickness), it was first described in 1917 by neurologist Constantin von Economo [2] [3] and pathologist Jean-René Cruchet. [4]
Encephalitis with meningitis is known as meningoencephalitis, while encephalitis with involvement of the spinal cord is known as encephalomyelitis. [ 2 ] The word is from Ancient Greek ἐγκέφαλος , enképhalos 'brain', [ 37 ] composed of ἐν , en , 'in' and κεφαλή , kephalé , 'head', and the medical suffix -itis 'inflammation'.
The encephalitis lethargica epidemic lasted from around 1918 to 1930. [1] The cause is still unknown. [2] Though the cause was once attributed to the coinciding Spanish flu epidemic, modern research has disputed this claim. [3] The mortality was as high as 20%. [4]
1919–1930 encephalitis lethargica epidemic: 1919–1930 Worldwide Encephalitis lethargica: 500,000 [191] [192] [193] 1924 Los Angeles pneumonic plague outbreak: 1924 Los Angeles, United States Pneumonic plague: 30 [194] 1924–1925 Minnesota smallpox epidemic: 1924–1925 Minnesota, United States Smallpox: 500 [195] 1927 Montreal typhoid ...
Historically, starting in 1917 an epidemic of encephalitis lethargica, also called von Economo's encephalitis or "sleepy-disease" occurred, possibly related to the 1918 Spanish flu pandemic; however, even with the use of modern molecular diagnostic tests on appropriate corpses, no firm link between encephalitis lethargica and influenza has been ...
Awakenings is a 1973 non-fiction book by Oliver Sacks.It recounts the life histories of those who had been victims of the 1920s encephalitis lethargica epidemic. [1] Sacks chronicles his efforts in the late 1960s to help these patients at the Beth Abraham Hospital (now Beth Abraham Center for Rehabilitation and Nursing) in the Bronx, New York. [2]
A human case of Eastern equine encephalitis was identified in Massachusetts for the first time since 2020. Now the state's public health department is ringing the alarm in multiple communities to ...
In 1969, Dr. Malcolm Sayer is a dedicated and caring physician at a local hospital in the New York City borough of the Bronx.After working extensively with the catatonic patients who survived the 1919–1930 epidemic of encephalitis lethargica, Sayer discovers that certain stimuli will reach beyond the patients' respective catatonic states.