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Encephalitis lethargica is an atypical form of encephalitis.Also known as "sleeping sickness" or "sleepy sickness" (distinct from tsetse fly–transmitted sleeping sickness), it was first described in 1917 by neurologist Constantin von Economo [2] [3] and pathologist Jean-René Cruchet. [4]
Encephalitis lethargica is identified by high fever, headache, delayed physical response, and lethargy. Individuals can exhibit upper body weakness, muscular pains, and tremors, though the cause of encephalitis lethargica is not currently known. From 1917 to 1928, an epidemic of encephalitis lethargica occurred worldwide. [10]
Historically, starting in 1917 an epidemic of encephalitis lethargica, also called von Economo's encephalitis or "sleepy-disease" occurred, possibly related to the 1918 Spanish flu pandemic; however, even with the use of modern molecular diagnostic tests on appropriate corpses, no firm link between encephalitis lethargica and influenza has been ...
Encephalitis lethargica is a neurological syndrome that causes lethargy, a “mask like” face, excessive blood in the meninges, and other general neurological symptoms. [5] Officially recognized as its own condition in 1917, it is believed to have existed far longer in human history. [5] It is known to cause post-encephalitic parkinsonism. [3]
There are currently no well-accepted treatments for the prevention or treatment of SAE symptoms, and treatment is largely symptom-based. [ 1 ] [ 5 ] In the acute phase, certain medications may aggravate symptoms and may be avoided, such as anticholinergics , antihistamines , sedatives , benzodiazepines , antipsychotics , and anticonvulsants (in ...
What Are the Symptoms of RSV in Older Adults? Symptoms of RSV can range from mild to severe. Dr. Elizalde says that mild RSV symptoms can include a runny nose, sore throat, coughing, sneezing and ...
Klazomania (from the Greek κλάζω ("klazo")—to scream) refers to compulsive shouting; [1] it has features resembling the complex tics such as echolalia, palilalia and coprolalia seen in tic disorders, but has been seen in people with encephalitis lethargica, alcohol use disorder, and carbon monoxide poisoning. [2]
Acute - the most common diseases caused by acute viral infections are encephalitis, flaccid paralysis, aseptic meningitis, post infectious and encephalomyelitis.; Chronic - the most common diseases caused by chronic viral infections are subacute-sclerosing panencephalitis, progressive multifocal leukoencephalopathy, retrovirus disease and spongiform encephalopathies.