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  2. Trodusquemine - Wikipedia

    en.wikipedia.org/wiki/Trodusquemine

    Trodusquemine is an aminosterol (polyamine steroid conjugate) that inhibits protein tyrosine phosphatase 1B (PTP1B) activity. [1] The compound exhibits broad-spectrum antimicrobial activity [2] and numerous regenerative, neuroprotective, anti-atherosclerotic, antitumor, antiangiogenic, antiobesity, and anxiolytic properties. [3]

  3. Single-domain antibody - Wikipedia

    en.wikipedia.org/wiki/Single-domain_antibody

    A single-domain antibody is a peptide chain of about 110 amino acids long, comprising one variable domain (V H) of a heavy-chain antibody, or of a common IgG.These peptides have similar affinity to antigens as whole antibodies, but are more heat-resistant and stable towards detergents and high concentrations of urea.

  4. Anti-interleukin-6 - Wikipedia

    en.wikipedia.org/wiki/Anti-interleukin-6

    The first approved medication in this class, tocilizumab (Actemra), is an antibody directed against the IL6-receptor. [8] The second, siltuximab (Sylvant), is directed against IL-6 itself. [ 1 ] [ 9 ] Siltuximab is approved for treatment of human immunodeficiency virus-negative and HHV-8 -negative patients with multicentric Castleman's disease .

  5. Antibody-oligonucleotide conjugate - Wikipedia

    en.wikipedia.org/wiki/Antibody-oligonucleotide...

    A straightforward uptake, like for most small-molecule drugs, is hindered by the polyanionic backbone and the molecular size of ONs. Being adapted from the broad and successful class of Antibody-Drug conjugates , antibodies and antibody analogues are more and more used in research in order to overcome hurdles related to delivery and ...

  6. Galcanezumab - Wikipedia

    en.wikipedia.org/wiki/Galcanezumab

    In September 2018, galcanezumab was approved in the United States for the preventive treatment of migraine in adults. [9] [10] The FDA granted the approval of Emgality to Eli Lilly. [9] [10] In November 2018, galcanezumab was approved for use in the European Union for the prophylaxis of migraine in adults who have at least four migraine days ...

  7. Everything you need to know about the Mayo Clinic diet - AOL

    www.aol.com/lifestyle/everything-know-mayo...

    The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...