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Spinal disc herniation: Asymmetrical compression of an intervertebral disc ruptures the sac-like disc, causing a herniation of its soft content. The hernia compresses the adjacent nerves and causes back pain.
grade 1: the cartilage has a soft spot, blisters, or superficial wear; grade 2: minor tears of less than one-half the thickness of the cartilage layer; grade 3: lesions have deep crevices of more than one-half the thickness of the cartilage layer; grade 4: the cartilage tear is full thickness and exposes the underlying (subchondral) bone
Degenerative disc disease can result in lower back or upper neck pain. The amount of degeneration does not correlate well with the amount of pain patients experience. Many people experience no pain while others, with the same amount of damage have severe, chronic pain. [2]
The disc spaces, facet and sacroiliac joints remain unaffected. Diagnosis requires confluent ossification of at least four contiguous vertebral bodies. [ 2 ] Classically, advanced disease may have "melted candle wax" appearance along the spine on radiographic studies. [ 13 ]
A spotted gar larva at 22 days stained for cartilage (blue) and bone (red). Chondrogenesis is the biological process through which cartilage tissue is formed and developed. . This intricate and tightly regulated cellular differentiation pathway plays a crucial role in skeletal development, as cartilage serves as a fundamental component of the embryonic skele
Delayed onset Lhermitte's sign has been reported following head and/or neck trauma. [ 9 ] [ 10 ] This occurs ~2 1/2 months following injury, without associated neurological symptoms or pain, and typically resolves within 1 year.
Chondromalacia patellae (also known as CMP) is an inflammation of the underside of the patella and softening of the cartilage.. The cartilage under the kneecap is a natural shock absorber, and overuse, injury, and many other factors can cause increased deterioration and breakdown of the cartilage.
Chondrodystrophy has an autosomal recessive pattern of inheritance.. Chondrodystrophy is an autosomal recessive disorder, meaning that in order for this disease to be expressed, the affected individual must possess two copies of the allele for the disorder.