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Maggot therapy (also known as larval therapy) is a type of biotherapy involving the introduction of live, disinfected maggots (fly larvae) into non-healing skin and soft-tissue wounds of a human or other animal for the purpose of cleaning out the necrotic (dead) tissue within a wound (debridement), and disinfection.
Gangrene is a type of tissue death caused by a lack of blood supply. [4] The feet and hands are most commonly affected. [1] If the gangrene is caused by an infectious agent, it may present with a fever or sepsis. [1] Symptoms may include: [1] a change in skin color to red or black; numbness; swelling; pain; skin breakdown; coolness
Debridement is the medical removal of dead, damaged, or infected tissue to improve the healing potential of the remaining healthy tissue. [ 2 ] [ 3 ] Removal may be surgical , mechanical, chemical, autolytic (self-digestion), or by maggot therapy .
It mostly occurs in patients with underlying immunocompromise (e.g. malignancy or HIV). Although most cases are due to P. aeruginosa infection, recent reports of this skin lesion associate it with other microorganisms, such as Escherichia coli , Citrobacter freundii , Klebsiella pneumoniae , various other Pseudomonas species, and Morganella ...
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
Hydrocolloid dressings are used to treat uninfected wounds. [6] Dressings may be used, under medical supervision, even where aerobic infection is present; the infection should be treated appropriately. [citation needed] The dressing is applied to a cleaned wound. Hydrocolloid patches are sometimes used on the face for acne.
Pyoderma gangrenosum ulcers demonstrate pathergy, that is, a worsening in response to minor trauma or surgical debridement. Significant care should be taken with dressing changes to prevent potentially rapid wound growth.
A woman recovering from knee surgery suffered a persistent infection of the knee with Pasteurella after her dog licked a small wound on her toe. [62] [63] A dog lick to an Australian woman's minor burn caused sepsis and necrosis due to Capnocytophaga canimorsus infection, resulting in the loss of all her toes, fingers and a leg. [64] [65]