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Lipolysis / l ɪ ˈ p ɒ l ɪ s ɪ s / is the metabolic pathway through which lipid triglycerides are hydrolyzed into a glycerol and free fatty acids. It is used to mobilize stored energy during fasting or exercise , and usually occurs in fat adipocytes .
The supplement tricaprin, which is found in coconut or MCT oil, improved long-term survival for people with triglyceride deposit cardiomyovasculopathy, according to the results of a recent study.
Gemfibrozil increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipoprotein triglyceride lipolysis. It does so by activating peroxisome proliferator-activated receptor alpha (PPARα) 'transcription factor ligand', a receptor that is involved in metabolism of carbohydrates and fats, as well as adipose tissue ...
Lipaemia retinalis is a retinal disease caused by hypertriglyceridemia or chylomicronemia. [3] Depending on plasma triglyceride level, the retinal arteries, veins or occasionally the entire fundus may show creamy-white to salmon red discoloration. [6]
Hypertriglyceridemia is the presence of high amounts of triglycerides in the blood.Triglycerides are the most abundant fatty molecule in most organisms. Hypertriglyceridemia occurs in various physiologic conditions and in various diseases, and high triglyceride levels are associated with atherosclerosis, even in the absence of hypercholesterolemia (high cholesterol levels) and predispose to ...
Fenofibrate (sold under the brand name Tricor among others), is an oral medication of the fibrate class used to treat abnormal blood lipid levels. [3] It is less commonly used compared to statins because it treats a different type of cholesterol abnormality to statins.
Treatment for familial hypertriglyceridemia should focus primarily on reducing serum triglyceride levels. If an individual has co-morbid conditions, ensuring that they are adequately addressed will aid in obtaining a more normal baseline lipid panel.
Tricaprin has been indicated as a possible drug to increase the production of insulin and decrease the production of androgen in the body when taken orally. [11] It, along with other medium-chain triglycerides, has been studied as a treatment option to prevent ruptures of abdominal aortic aneurysm, [12] and has been specifically studied as a regulator of membrane functions [13] and in the ...