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neglected squamous cell carcinoma skin of scalp Advanced squamous cell carcinoma, excision specimen. Note invasion subcutaneous tissue. Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma.
A squamous intraepithelial lesion (SIL) is an abnormal growth of epithelial cells on the surface of the cervix, commonly called squamous cells. This condition can lead to cervical cancer , but can be diagnosed using a Pap smear or a colposcopy .
All squamous cell carcinoma lesions are thought to begin via the repeated, uncontrolled division of cancer stem cells of epithelial lineage or characteristics. Accumulation of these cancer cells causes a microscopic focus of abnormal cells that are, at least initially, locally confined within the specific tissue in which the progenitor cell resided.
Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. [1] These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts .
Squamous hyperplasia; Low-grade penile intraepithelial neoplasia (PIN); High-grade PIN (carcinoma in situ—Bowen's disease, Erythroplasia of Queyrat and bowenoid papulosis (BP)); Invasive carcinoma of the penis. However, in some cases, non-dysplastic or mildly dysplastic lesions may progress directly into cancer.
Lymphocytic esophagitis is a rare and poorly understood medical disorder involving inflammation in the esophagus.The disease is named from the primary inflammatory process, wherein lymphocytes are seen within the esophageal mucosa.
These are called Marjolin's ulcers based on their appearance, and can develop into squamous-cell skin cancer. Ionizing radiation such as X-rays, environmental carcinogens, and artificial UV radiation (e.g. tanning beds). [30] It is believed that tanning beds are the cause of hundreds of thousands of basal and squamous-cell skin cancer. [33]
Marjolin's ulcer refers to an aggressive ulcerating squamous cell carcinoma presenting in an area of previously traumatized, [1] chronically inflamed, [2] or scarred skin. [3]: 737 [4] They are commonly present in the context of chronic wounds including burn injuries, varicose veins, venous ulcers, [5] ulcers from osteomyelitis, [6] and post radiotherapy scars.