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Digitalis lanata, vernacularly often called woolly foxglove [3] or Grecian foxglove, [4] is a species of foxglove, a flowering plant in the plantain family Plantaginaceae. It gets its name due to the woolly indumentum of the leaves. D. lanata, like other foxglove species, is toxic in all parts of the plant. Symptoms of digitalis poisoning ...
Digitalis (/ ˌ d ɪ dʒ ɪ ˈ t eɪ l ɪ s / [3] or / ˌ d ɪ dʒ ɪ ˈ t æ l ɪ s / [4]) is a genus of about 20 species of herbaceous perennial plants, shrubs, and biennials, commonly called foxgloves. Digitalis is native to Europe, Western Asia, and northwestern Africa. The flowers are tubular in shape, produced on a tall spike, and vary in ...
Its use was somewhat sporadic until Sir James Mackenzie identified the phenomenon of atrial fibrillation, and the actions of digitalis on this. [47] Its effects were first explained by Arthur Robertson Cushny. [48] The name is a portmanteau, derived from Digitalis lanata and toxin. [49]
Digitalis lanata: Digitalis or foxglove It came into use in treating cardiac disease in late 18th century England in spite of its high toxicity. a Its use has been almost entirely replaced by the pharmaceutical derivative Digoxin, which has a shorter half-life in the body, and whose toxicity is therefore more easily managed. [54]
α-Acetyldigoxin is a cardiac glycoside found in plants of the genus Digitalis, including Digitalis lanata. [1] It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin. α-Acetyldigoxin increases the contractility of the heart by its positive inotropic effect on cardiac muscle.
Lanatoside C can be used orally [1] or by the intravenous route. [2] It is marketed in a number of countries and is also available in generic form. [3] Its main indications are rapid response atrial fibrilation and paroxysmal supraventricular tachycardia, [citation needed] two common types of arrhythmia. It is found in Digitalis lanata. [4]
Digitalis lanata and Digitalis purpurea (Woolly and purple foxglove): digoxin, ... Thus, though cardiac glycosides have been used for their medicinal function, their ...
Edgbaston Hall. Born in England, Withering attended Edinburgh Medical School from 1762 to 1766. In 1767 he started as a consultant at Stafford Royal Infirmary. He married Helena Cookes (an amateur botanical illustrator, and a former patient of his) in 1772; they had three children (the first, Helena was born in 1775 but died a few days later, William was born in 1776, and Charlotte in 1778).